pMel17 is recognised by monoclonal antibodies NKI-beteb, HMB-45 and HMB-50 and by anti-melanoma CTL
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چکیده
منابع مشابه
Expression of microphthalmia transcription factor, S100 protein, and HMB-45 in malignant melanoma and pigmented nevi
Malignant melanoma (MM) is a type of malignant tumor, which originates from neural crest melanocytes. MM progresses rapidly and results in a high mortality rate. The present study aims to investigate the expression of microphthalmia transcription factor (MITF), the S100 protein, and HMB-45 in MM and pigmented nevi. A total of 32 MM samples (including three skin metastasis, three lymph node meta...
متن کاملA primary amelanotic melanoma of the vagina, diagnosed by immunohistochemical staining with HMB-45, which recurred as a pigmented melanoma.
Usually, malignant melanoma is readily diagnosed by the presence of melanin granules. Although amelanotic melanoma contains a few melanin granules, it is often difficult to differentiate from non-epithelial malignant tumours. This report describes a case of amelanotic melanoma of the vagina, which was originally suspected to be a non-epithelial malignant tumour, but was subsequently correctly d...
متن کاملHuman eccrine sweat gland. Expression of neuroglandular antigens and coexpression of intermediate filaments.
Acrosyringium, duct and secretory epithelium as well as myoepithelial cells of human eccrine sweat glands have been characterized by different immunostaining patterns with mono- and polyclonal antibodies to a wide spectrum of tissue antigens. Using monoclonal antibodies to neuron-specific enolase (NSE) and melanoma-associated antigens (LS 59, HMB-45, NKI/C-3) the expression of neuroectodermal a...
متن کاملExpression of Bcl-2, Melan A and HMB-45 in Dysplastic Nevi.
BACKGROUND From the first recognition of dysplastic nevi as a pathology per se, many debates have been raised and many histological and immunohistological studies have been conducted in order to establish the true significance of these lesions. Therefore, the aim of this study was to establish if there is a correlation between HMB-45, Melan A and Bcl-2 expression and the grade of dysplasia, as ...
متن کاملHMB-45 negative angiomyolipoma of the orbit: a case report and review of the literature
BACKGROUND Angiomyolipoma is a benign mesenchymal tumor composed of variable amounts of smooth muscle, adipose tissue and thick-walled blood vessels, and usually named PEComas (perivascular epithelioid cell tumors). PEComas share overlapping histopathological features with epithelioid cells along a perivascular distribution and characteristic immunohistochemistry with coexpression of myoid and ...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1996
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1996.202